Crossing the blood–brain barrier with carbon dots: uptake mechanism and<i>in vivo</i>cargo delivery
Elif S. Seven, Yasin B. Seven, Yiqun Zhou, Sijan Poudel-Sharma, Juan J. Diaz-Rucco, Emel Kirbas Cilingir, Gordon S. Mitchell, J. David Van Dyken, Roger M. Leblanc
Abstract
ventral horn, dorsal horn, and middle grey) of the cervical spinal cord consistent with neuronal accumulation. Therefore, neuron targeting GluCDs hold tremendous potential as a drug delivery platform in neurodegenerative disease, traumatic injury, and malignancies of the CNS.
Topics & Concepts
Mechanism (biology)Blood–brain barrierIn vivoNanotechnologyChemistryNeuroscienceBiologyMaterials sciencePhysicsCentral nervous systemBiotechnologyQuantum mechanicsCarbon and Quantum Dots ApplicationsGraphene and Nanomaterials ApplicationsHeavy Metal Exposure and Toxicity