A Prospective, Randomized, Controlled, Multicenter Evaluation of Extraction Socket Management Comparing a Wound Dressing and a Soft Tissue Substitute
Diego Velásquez, Maurício G. Araújo, Donald S. Clem, John C. Gunsolley, Rick Heard, Jim Janakievski, Pamela K. McClain, Michael A. McGuire, Craig M. Misch, Marc L. Nevins, Steve Pickering, Bryan Pope, Chris G. Richardson, Greg A. Santarelli, E Scheyer, Rachel Schallhorn, Gregory Toback
Abstract
Diego Velasquez, DDS, MSD/Mauricio G. Araújo, DDS, MSc, PhD/Donald S. Clem, DDS/John C. Gunsolley, DDS, MS/Rick H. Heard, DDS, MS/Jim Janakievski, DDS, MSD/Pamela K. McClain, DDS/Michael K. McGuire, DDS/Craig M. Misch, DDS, MDS/Marc Nevins, DDS, MMSc/Steve Pickering, DDS, MSD/Bryan Pope, DDS, MSD/Chris Richardson, DMD, MS/Greg Santarelli, DDS/E. Todd Scheyer, DDS, MS/Rachel Schallhorn, DDS, MS/Gregory Toback, DDS, MS: Postextraction bone grafting and implant placement help preserve alveolar bone volume. Collagen wound dressings and soft tissue graft substitutes may help protect extraction socket bone grafts and provide better gingival contours. This randomized, controlled, multicenter, and double-blinded study was conducted to compare a control (wound dressing) and a test (soft tissue graft) substitute in nearly intact extraction sockets. Both test and control sockets were grafted with a xenogeneic bone graft. Graft containment, extraction socket soft tissue gap closure, gingival contour, and gingival thickness were examined over 16 weeks, at which time implants were placed. Healing was uneventful for both groups, and there was no significant difference (P < .05) between the times required to close the extraction socket soft tissue gap (~80% of sites closed by 8 weeks). Bone grafts were covered and contained longer in the test group (~4 weeks vs ~2 weeks), with less contour disruption out to 4 weeks; however, at implant placement, soft tissue contours in both groups were comparable, and soft tissue thicknesses were not significantly different.