Si-Ni-San inhibits hepatic Fasn expression and lipid accumulation in MAFLD mice through AMPK/p300/SREBP-1c axis
Tian Lan, Xiaojuan Geng, Si-jia Zhang, Xi-xi Zeng, Junjie Ying, Yi Xu, Shiyu Liu, Ping Li, Yuhua Tong, Wen Wang, Zhu-Jun Mao, Siwei Wang
Topics & Concepts
AMPKFatty acid synthaseLipid metabolismSterol regulatory element-binding proteinFatty liverAdenosine monophosphateAMP-activated protein kinaseProtein kinase AAdenosine triphosphateChemistryEndocrinologyInternal medicineBiologyAdenosineKinaseBiochemistryCholesterolMedicineSterolDiseaseLiver Disease Diagnosis and TreatmentDrug-Induced Hepatotoxicity and ProtectionSilymarin and Mushroom Poisoning