The long road to the first FDA-approved gene therapy: chimeric antigen receptor T cells targeting CD19
Peter Brændstrup, Bruce L. Levine, Marco Ruella
Topics & Concepts
Chimeric antigen receptorMedicineCD19BlinatumomabImmunotherapyImmunologyCytokine release syndromeLymphomaClinical trialCell therapyAntigenOncologyImmune systemCancer researchInternal medicineCellBiologyGeneticsCAR-T cell therapy researchVirus-based gene therapy researchCRISPR and Genetic Engineering