Litcius/Paper detail

Cancer Patients with COVID-19: A Retrospective Study of 51 Patients in the District of Piacenza, Northern Italy

Luigi Cavanna, Chiara Citterio, Ilaria Toscani, Cosimo Franco, Andrea Magnacavallo, Serena Caprioli, Evelina Cattadori, Camilla Di Nunzio, Roberto Pane, Roberta Schiavo, Claudia Biasini, Massimo Ambroggi

2020Future Science OA21 citationsDOIOpen Access PDF

Abstract

BACKGROUND: Cancer patients are considered a highly fragile group in the current coronavirus disease 2019 (COVID-19) pandemic. MATERIAL & METHODS: In this study, patients with COVID-19 and cancer, hospitalized in Piacenza, Italy, from 4 April to 4 May 2020 were included. Risk factors for death were analyzed. RESULTS: Fifty-one COVID-19 cancer patients were included, of which the median age was 71.02 years (range: 51-86) and 70.59% were male. Cancer types included gastrointestinal (25.49%), genitourinary (25.49%) and lung (23.53%). Forty-five (88.24%) patients received hydroxychloroquine-based therapy. In addition, 25 of 51 patients died (49%): 12 of 51 (23.53%) owing to cancer and 13 of 51 (25.49%) owing to COVID-19. CONCLUSION: The risks for death were related to later onset of treatment for COVID-19, severe/critical COVID-19, age, elevated basal CRP and elevated lactate dehydrogenase.

Topics & Concepts

MedicineLung cancerCancerInternal medicineHydroxychloroquineCoronavirus disease 2019 (COVID-19)GastroenterologyDiseaseInfectious disease (medical specialty)COVID-19 and healthcare impactsCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19