CDK2 heterobifunctional degraders co-degrade CDK2 and cyclin E resulting in efficacy in CCNE1-amplified and overexpressed cancers

Nicholas Kwiatkowski, Tong Liang, Zhe Sha, Philip N. Collier, A.K.M. Shamsuddin and Guang-Yu Yang, Murugappan Sathappa, Atanu Paul, Lijing Su, Xiaozhang Zheng, Robert J. Aversa, Kunhua Li, Revonda Mehovic, Christina Kolodzy, Susanne B. Breitkopf, Dapeng Chen, C Howarth, Karen Yuan, Hakryul Jo, Joseph D. Growney, Matthew M. Weiss, Juliet Williams