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Advancing the understanding of PFAS-induced reproductive toxicity in key model species

Ran Tao, Mingliang Sun, Jiateng Ma, Jiali Li, Xinni Yao, Minjie Li, Liang‐Hong Guo

2025Environmental Science Processes & Impacts6 citationsDOIOpen Access PDF

Abstract

are well-suited for examining chronic toxicity at environmentally relevant exposure levels, with their high-throughput screening capacity enabling efficient and low-cost assessment of transgenerational effects. In summary, this study systematically reviews the reproductive toxicity of PFASs in model organisms, offering a scientific foundation for optimizing model selection, exploring intervention strategies, and shaping future research directions.

Topics & Concepts

Key (lock)Reproductive toxicityToxicityEnvironmental scienceEnvironmental chemistryToxicologyBiologyChemistryEcologyMedicineInternal medicinePer- and polyfluoroalkyl substances researchFolate and B Vitamins ResearchEffects and risks of endocrine disrupting chemicals
Advancing the understanding of PFAS-induced reproductive toxicity in key model species | Litcius