Beyond association: high neutrophil counts are a causal risk factor for atherosclerotic cardiovascular disease
Oliver Soehnlein, Yvonne Döring
Abstract
Peripheral artery diseaseDegranulation NET release ROS productionFactors leading to increases in neutrophil counts and neutrophil-mediated mechanisms fostering atherosclerotic cardiovascular disease (ACVD).NET, neutrophil extracellular trap; ROS, reactive oxygen species.This figure was made with BioRender.com.
Topics & Concepts
MedicineAngiologyUniversity hospitalImpact factorLibrary scienceFamily medicineGerontologyInternal medicineLawComputer sciencePolitical scienceAtherosclerosis and Cardiovascular DiseasesNeutrophil, Myeloperoxidase and Oxidative MechanismsAdipokines, Inflammation, and Metabolic Diseases