Blocking cGAS-STING pathway promotes post-stroke functional recovery in an extended treatment window via facilitating remyelination
Munire Maimaiti, Chenhui Li, Mingxing Cheng, Ziwei Zhong, Jiameng Hu, Lei Yang, Lele Zhang, Ze Hong, Jinyi Song, Mingyu Pan, Xiaonan Ma, Shufang Cui, Peng Zhang, Haiping Hao, Chen Wang, Hai Hu
Topics & Concepts
RemyelinationStimulator of interferon genesStingTherapeutic windowMedicineActivator (genetics)Immune systemSignal transductionBiologyImmunologyCell biologyNeurosciencePharmacologyGeneInnate immune systemGeneticsCentral nervous systemMyelinAerospace engineeringEngineeringinterferon and immune responsesNeuroinflammation and Neurodegeneration MechanismsRNA regulation and disease