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Recent advances in understanding the role of eosinophils

Gregory Constantine, Amy D. Klion

2022Faculty Reviews23 citationsDOIOpen Access PDF

Abstract

Our understanding of eosinophil biology, development, and regulation has dramatically increased in the past decade, leading to new paradigms for the role of eosinophils in human health and disease and, perhaps more importantly, providing insights toward novel treatment strategies in the fight against eosinophil-mediated inflammation. In this review, we discuss recent advances regarding the role of eosinophils in host-viral defense, eosinophil heterogeneity, and eosinophil-targeted therapies.

Topics & Concepts

EosinophilImmunologyDiseaseInflammationBiologyMedicineNeurosciencePathologyAsthmaAsthma and respiratory diseasesEosinophilic Disorders and SyndromesImmune Cell Function and Interaction