Ugi reaction-assisted assembly of covalent PROTACs against glutathione peroxidase 4
Liquan Zhu, Shiqi Hu, Xiaoqiao Yan, Qian Zeng, Bei Zhang, Linye Jiang, Shao Q. Yao, Jingyan Ge
Topics & Concepts
ChemistryGPX4ProteasomeBiochemistryUbiquitin ligaseUbiquitinProteolysisGlutathioneCell biologyGlutathione peroxidaseEnzymeBiologyGenePeptidase Inhibition and AnalysisProtein Degradation and InhibitorsHistone Deacetylase Inhibitors Research