Litcius/Paper detail

Establishment of human fetal hepatocyte organoids and CRISPR–Cas9-based gene knockin and knockout in organoid cultures from human liver

Delilah Hendriks, Benedetta Artegiani, Huili Hu, Susana M. Chuva de Sousa Lopes, Hans Clevers

2020Nature Protocols156 citationsDOIOpen Access PDF

Topics & Concepts

OrganoidCRISPRBiologyCell biologyGenome editingHepatocyteGene knockoutGeneGeneticsIn vitroCRISPR and Genetic EngineeringPluripotent Stem Cells ResearchRenal and related cancers