Metformin attenuates the epithelial-mesenchymal transition of lens epithelial cells through the AMPK/TGF-β/Smad2/3 signalling pathway
Ling Wang, Ye Tian, Zhiqun Shang, Boya Zhang, Xia Hua, Xiaoyong Yuan
Topics & Concepts
AMPKPhosphorylationEpithelial–mesenchymal transitionCell biologyHedgehog signaling pathwaySignal transductionCancer researchFibrosisProtein kinase Ap38 mitogen-activated protein kinasesBiologyChemistryDownregulation and upregulationInternal medicineMedicineGeneBiochemistryFibroblast Growth Factor ResearchTGF-β signaling in diseasesMetabolism, Diabetes, and Cancer