Regulation of macrophage polarization through surface topography design to facilitate implant-to-bone osteointegration
Yizhou Zhu, Hang Liang, Xiangmei Liu, Jun Wu, Yang Cao, Tak Man Wong, Kenny Kwan, Kmc Cheung, Shuilin Wu, Kwk Yeung
Abstract
), which reinforced the polarization of macrophages through the activation of the RhoA/Rho-associated protein kinase signaling pathway.
Topics & Concepts
OsseointegrationMacrophage polarizationImplantNanostructureImmune systemMaterials scienceMacrophageNanotechnologyBiomedical engineeringBiologyMedicineImmunologyIn vitroBiochemistrySurgeryBone Tissue Engineering MaterialsGraphene and Nanomaterials ApplicationsNanoparticle-Based Drug Delivery