Oleic and linoleic acids promote chondrocyte apoptosis by inhibiting autophagy via downregulation of SIRT1/FOXO1 signaling
Xiaodong Li, Chen Zhao, Chuanyuan Mao, Guantong Sun, Fei Yang, Lei Wang, Xiaoqing Wang
Topics & Concepts
ChondrocyteAutophagyFOXO1Downregulation and upregulationChemistryOleic acidLinoleic acidCell biologyOsteoarthritisApoptosisBiochemistryInternal medicineCancer researchEndocrinologyFatty acidBiologyMedicineProtein kinase BIn vitroPathologyGeneAlternative medicineOsteoarthritis Treatment and MechanismsAdipose Tissue and MetabolismCancer-related molecular mechanisms research