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An application of the ensemble Kalman filter in epidemiological modelling

Rajnesh Lal, Weidong Huang, Zhenquan Li

2021PLoS ONE26 citationsDOIOpen Access PDF

Abstract

Since the novel coronavirus (COVID-19) outbreak in China, and due to the open accessibility of COVID-19 data, several researchers and modellers revisited the classical epidemiological models to evaluate their practical applicability. While mathematical compartmental models can predict various contagious viruses' dynamics, their efficiency depends on the model parameters. Recently, several parameter estimation methods have been proposed for different models. In this study, we evaluated the Ensemble Kalman filter's performance (EnKF) in the estimation of time-varying model parameters with synthetic data and the real COVID-19 data of Hubei province, China. Contrary to the previous works, in the current study, the effect of damping factors on an augmented EnKF is studied. An augmented EnKF algorithm is provided, and we present how the filter performs in estimating models using uncertain observational (reported) data. Results obtained confirm that the augumented-EnKF approach can provide reliable model parameter estimates. Additionally, there was a good fit of profiles between model simulation and the reported COVID-19 data confirming the possibility of using the augmented-EnKF approach for reliable model parameter estimation.

Topics & Concepts

Ensemble Kalman filterKalman filterCoronavirus disease 2019 (COVID-19)EstimationComputer scienceEstimation theoryFilter (signal processing)Data assimilationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Extended Kalman filterEconometricsData miningStatisticsAlgorithmMathematicsArtificial intelligenceGeographyEngineeringMedicineMeteorologyDiseaseSystems engineeringPathologyInfectious disease (medical specialty)Computer visionCOVID-19 epidemiological studiesData-Driven Disease SurveillanceMathematical and Theoretical Epidemiology and Ecology Models
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