Heart failure as a complication of COVID-19 infection: systematic review and meta-analysis
Marco Zuin, Gianluca Rigatelli, Claudio Bilato, Giovanni Zuliani, Loris Roncon
Abstract
BACKGROUND/OBJECTIVES: The prevalence and prognostic implications of heart failure (HF), as a complication of COVID-19 infection remains unclear. We performed a systematic review and metanalysis aimed to evaluate the pooled incidence of acute HF as a cardiac complication of COVID-19 disease and to estimate the related mortality risk in these patients. METHODS: Data were obtained searching MEDLINE, Scopus and Web of Science for all investigations published any time to 26 December 2020. If statistical heterogeneity was 50%, the results were derived from the fixed-effects model otherwise the random-effects model. RESULTS: = 0.053). CONCLUSIONS: Acute HF represents a frequent complication of COVID-19 infection associated with a higher risk of mortality in the short-term period.