Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer
Tamara Ouspenskaia, Travis Law, Karl R. Clauser, Susan Klaeger, Siranush Sarkizova, François Aguet, Bo Li, Elena Christian, Binyamin A. Knisbacher, Phuong M. Le, Christina R. Hartigan, Hasmik Keshishian, Annie Apffel, Giacomo Oliveira, Wandi Zhang, Sarah Chen, Yuen Ting Chow, Zhe Ji, Irwin Jungreis, Sachet A. Shukla, Sune Justesen, Pavan Bachireddy, Manolis Kellis, Gad Getz, Nir Hacohen, Derin B. Keskin, Steven A. Carr, Catherine J. Wu, Aviv Regev
Topics & Concepts
Cancer immunotherapyBiologyMajor histocompatibility complexEpitopeComputational biologyMHC class IImmune systemSomatic cellAntigenMolecular biologyImmunotherapyCancer researchGeneticsGenevaccines and immunoinformatics approachesImmunotherapy and Immune ResponsesPeptidase Inhibition and Analysis