Antimicrobial Nanogels with Nanoinjection Capabilities for Delivery of the Hydrophobic Antibacterial Agent Triclosan
Guangyue Zu, Magdalena Steinmüller, Damla Keskin, Henny C. van der Mei, Olga Mergel, Patrick van Rijn
Abstract
decreased 3 orders of magnitude, compared to free Triclosan. The synergy of physical destruction and active nanoinjection significantly enhances the antimicrobial efficacy, and the designed nanoinjection delivery system holds great promise for combating antimicrobial resistance as well as the applications of hydrophobic drugs delivery for many other possible applications.
Topics & Concepts
NanogelTriclosanAntimicrobialChemistryNanocarriersDrug deliveryHydrophobic effectCombinatorial chemistryOrganic chemistryMedicinePathologyAntimicrobial agents and applicationsAntimicrobial Peptides and ActivitiesGraphene and Nanomaterials Applications