Synthesis of Unsymmetrical 1,4-Dicarbonyl Compounds by Photocatalytic Oxidative Radical Additions
Ya Dong, Ruining Li, Junliang Zhou, Zhankui Sun
Abstract
Herein we report a photocatalytic oxidative radical addition reaction for the synthesis of unsymmetrical 1,4-dicarbonyl compounds. This reaction utilizes a desulfurization process to generate electrophilic radicals, which add to α-halogenated alkenes and undergo further oxidation to deliver 1,4-dicarbonyl compounds. This mild and highly efficient method provides a valuable alternative to known strategies.
Topics & Concepts
ChemistryPhotocatalysisRadicalElectrophileOxidative phosphorylationFlue-gas desulfurizationCombinatorial chemistryOrganic chemistryPhotochemistryCatalysisBiochemistryCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSulfur-Based Synthesis Techniques