Development of optic disc edema during 30 days of hypercapnic head-down tilt bed rest is associated with short sleep duration and blunted temperature amplitude
Kate H. Christian, Carla S. Petitti, Kyra Oretga-Schwartz, Edwin Mulder, Alexandra Noppe, Melanie von der Wiesche, Claudia Stern, Millennia Young, Brandon R. Macias, Steven S. Laurie, Andrew T. Lovering
Abstract
We determined that sleep and 24-h core body temperature were unaltered by 30 days exposure to the spaceflight analog strict 6° head-down tilt bed rest (HDTBR) in a 0.5% CO 2 environment. However, shorter sleep duration, greater wake after sleep onset, and lower core temperature amplitude present throughout the study were associated with the development of optic disc edema, a key finding of spaceflight-associated neuro-ocular syndrome.
Topics & Concepts
Head-Down TiltAnesthesiaMedicineBed restEdemaRest (music)CardiologyInternal medicineTraumatic Brain Injury and Neurovascular DisturbancesIntraoperative Neuromonitoring and Anesthetic EffectsNeurological Complications and Syndromes