Antimicrobial Susceptibilities of Clostridium difficile Isolates from 12 Asia-Pacific Countries in 2014 and 2015
Tanya Lew, Papanin Putsathit, Kyung Mok Sohn, Yuan Wu, Kentaro Ouchi, Yoshikazu Ishii, Kazuhiro Tateda, Thomas V. Riley, Deirdre A. Collins
Abstract
Clostridium ( Clostridioides ) difficile causes toxin-mediated diarrhea and pseudomembranous colitis, primarily among hospital inpatients. Outbreaks of C. difficile infection (CDI) have been caused by strains with acquired antimicrobial resistance, particularly fluoroquinolone resistance, including C. difficile ribotype (RT) 027 in North America and Europe and RT 017, the most common strain in Asia. Despite being the most common cause of hospital-acquired infection in high-income countries, and frequent misuse of antimicrobials in Asia, little is known about CDI in the Asia-Pacific region.
Topics & Concepts
Clostridium difficilePseudomembranous colitisDiarrheaMicrobiologyOutbreakAntimicrobialMedicineAntibiotic resistanceBiologyAntibioticsVirologyInternal medicineClostridium difficile and Clostridium perfringens researchNosocomial Infections in ICUAntimicrobial Resistance in Staphylococcus