m6A mRNA methylation regulates the ERK/NF-κB/AKT signaling pathway through the PAPPA/IGFBP4 axis to promote proliferation and tumor formation in endometrial cancer
Peng Ruan, Shujun Wang, Chaoyi Yang, Xiaohui Huang, Pengxing Sun, Aili Tan
Topics & Concepts
MethylationEndometrial cancerCancer researchRNA methylationGene knockdownProtein kinase BDNA methylationMAPK/ERK pathwayBiologyCancerSignal transductionOncologyMedicineGene expressionMethyltransferaseInternal medicineGeneCell biologyGeneticsRNA modifications and cancerCancer-related molecular mechanisms researchCancer-related gene regulation