Litcius/Paper detail

Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson–Gilford progeria syndrome

M. Puttaraju, Michaela Jackson, Stéphanie Klein, Asaf Shilo, C. Frank Bennett, Leslie B. Gordon, Frank Rigo, Tom Misteli

2021Nature Medicine76 citationsDOIOpen Access PDF

Topics & Concepts

ProgeriaLMNABiologyIn vivoRNA splicingOligonucleotideCell biologyCancer researchRNAGeneticsGeneMutationNuclear Structure and FunctionRNA Research and SplicingDNA Repair Mechanisms