Effects of high-intensity intermittent exercise on the contractile properties of human type I and type II skeletal muscle fibers
C. R. Lamboley, David Rouffet, T. L. Dutka, Michael J. McKenna, Graham D. Lamb
Abstract
This study identified important cellular changes occurring in human skeletal muscle fibers following high-intensity intermittent exercise: 1) a decrease in contractile apparatus Ca 2+ sensitivity in type I but not type II fibers, 2) a decrease in specific force only in type II muscle fibers, and 3) a redox-dependent increase in Ca 2+ sensitivity occurring only in type II fibers, which would help maintain muscle performance by countering the normal metabolite-induced decline in Ca 2+ sensitivity.
Topics & Concepts
Skeletal muscleChemistrySkeletal Muscle FibersMuscle contractionEndocrinologyBiophysicsInternal medicineIntensity (physics)BiologyMedicineQuantum mechanicsPhysicsExercise and Physiological ResponsesMuscle Physiology and DisordersAdipose Tissue and Metabolism