An altered heparan sulfate structure in the articular cartilage protects against osteoarthritis
Ann-Christine Severmann, Katja Jochmann, Konstantina Feller, Velina Bachvarova, Virginia Piombo, Richard Stange, Tatjana Holzer, Bent Brachvogel, Jeffrey D. Esko, Thomas Pap, Daniel Hoffmann, Andrea Vortkamp
Topics & Concepts
AggrecanZymographyMolecular biologyWestern blotProteasesCartilageChemistryChondrocyteOsteoarthritisBiologyBiochemistryPathologyMatrix metalloproteinaseMedicineAnatomyGeneEnzymeArticular cartilageAlternative medicineProteoglycans and glycosaminoglycans researchOsteoarthritis Treatment and MechanismsLiver physiology and pathology