Binding properties of flowing fibrin-targeted microbubbles evaluated with a thrombus-embedded microchannel
Jiang Li, Yuan Zhang, Chenghong Zou, Yuexin Chen, Yongjian Li, Haosheng Chen
Abstract
. This work not only provides an effective method for the fabrication of fibrin-targeted MBs based on commercially available SonoVue MBs but also demonstrates an approach for evaluation of the binding properties of flowing targeted MBs under well-controlled flow conditions.
Topics & Concepts
MicrochannelMicrobubblesThrombusFibrinBiomedical engineeringBlood flowChemistryBiophysicsMaterials scienceNanotechnologyCardiologyMedicineRadiologyUltrasoundImmunologyBiologyBlood properties and coagulationInnovative Microfluidic and Catalytic Techniques InnovationMicrofluidic and Bio-sensing Technologies