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The Short-Term Effect of Whey Compared with Pea Protein on Appetite, Food Intake, and Energy Expenditure in Young and Older Men

Aubree Hawley, Edward E. Gbur, Angela Tacinelli, Sam Walker, Allie Murphy, Regan Burgess, Jamie Baum

2020Current Developments in Nutrition18 citationsDOIOpen Access PDF

Abstract

BACKGROUND: Diets higher in protein have been reported to improve age-related changes in body composition via increased energy expenditure, shifts in substrate oxidation (SO), and decreased appetite. However, how protein source (e.g., animal compared with plant protein) affects energy expenditure, appetite, and food intake as we age is unknown. OBJECTIVES: The objective of this study was to evaluate the effect of protein source as part of a high-protein breakfast on appetite, food intake, energy expenditure, and fat oxidation in young men (YM) compared with older men (OM). METHODS: This study used a randomized, single-blinded crossover design, with a 1-wk washout period between testing days. Fifteen YM (mean ± SD age: 25.2 ± 2.8 y) and 15 OM (67.7 ± 4.5 y), healthy adults, participated in the study. Participants arrived fasted and consumed an isocaloric, volume-matched, high-protein (40-g) test beverage made with either an animal [whey protein isolate (WPI)] or plant [pea protein isolate (PPI)] protein isolate source. Markers of appetite and energy expenditure were determined at baseline and over 4 h postprandial. RESULTS: < 0.001) compared with YM. CONCLUSIONS: This study indicates that a high-protein breakfast containing WPI or PPI exerts comparable effects on appetite, energy expenditure, and 24-h energy intake in both young and older healthy adult men.This trial was registered at clinicaltrials.gov as NCT03399812.

Topics & Concepts

AppetiteCrossover studyEnergy expenditureWhey protein isolatePostprandialWhey proteinInternal medicineEndocrinologyMedicineAnimal scienceFood scienceChemistryBiologyInsulinPathologyAlternative medicinePlaceboMuscle metabolism and nutritionProteins in Food SystemsProtein Hydrolysis and Bioactive Peptides