The HDAC6 inhibitor 7b induces BCR-ABL ubiquitination and downregulation and synergizes with imatinib to trigger apoptosis in chronic myeloid leukemia
Hélène Losson, Sruthi Reddy Gajulapalli, Manon Lernoux, Jin‐Young Lee, Aloran Mazumder, Déborah Gérard, Carole Seidel, Hyunggu Hahn, Christo Christov, Mario Dicato, Gilbert Kirsch, Byung Woo Han, Michaël Schnekenburger, Marc Diederich
Topics & Concepts
Downregulation and upregulationCancer researchImatinibMyeloid leukemiaImatinib mesylateBosutinibTyrosine kinaseLeukemiaTyrosine-kinase inhibitorMedicineCancerBiologyImmunologyDasatinibInternal medicineReceptorGeneBiochemistryHistone Deacetylase Inhibitors ResearchChronic Myeloid Leukemia TreatmentsMultiple Myeloma Research and Treatments