Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies
Theodore L. Roth, P. Jonathan Li, Franziska Blaeschke, Jasper F. Nies, Ryan Apathy, Cody T. Mowery, Ruby Yu, Michelle Nguyen, Youjin Lee, Anna Truong, Joseph Hiatt, David Wu, David N. Nguyen, Daniel B. Goodman, Jeffrey A. Bluestone, Chun Ye, Kole T. Roybal, Eric Shifrut, Alexander Marson
Topics & Concepts
BiologyChimeric antigen receptorComputational biologyCRISPRImmunotherapyGenome editingTranscriptomeGeneImmune systemGeneticsGene expressionCAR-T cell therapy researchCRISPR and Genetic EngineeringSingle-cell and spatial transcriptomics