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Development of Genomic DNA Certified Reference Materials for Genetically Modified Rice Kefeng 6

Jun Li, Li Zhang, Liang Li, Xiaying Li, Xiujie Zhang, Shanshan Zhai, Hongfei Gao, Yunjing Li, Gang Wu, Yuhua Wu

2020ACS Omega21 citationsDOIOpen Access PDF

Abstract

copies/μL, respectively. The gDNA CRMs displayed good between-vial homogeneity when the minimum sample intake of 2 μL was taken into account. Stability studies indicated that the gDNA CRMs should be transported below 25 °C, and cold chain transport was recommended. Shelf life was assessed to be at least 12 months, and when using gDNA CRMs, freeze-thaw should not exceed 10 cycles. Compared to the available gDNA CRMs in the market, this batch of gDNA CRMs has accurate property values with combined uncertainties, providing user-friendly calibrators for GM rice Kefeng 6 inspection and monitoring. The development and characterization of Kefeng 6 gDNA CRMs contribute to the establishment of a copy number-based reference system for GMO detection.

Topics & Concepts

Certified reference materialsgenomic DNATraceabilityBiotechnologyFood scienceBiologyComputational biologyChemistryComputer scienceDNAChromatographyGeneticsDetection limitSoftware engineeringGenetically Modified Organisms ResearchCRISPR and Genetic EngineeringInsect Resistance and Genetics
Development of Genomic DNA Certified Reference Materials for Genetically Modified Rice Kefeng 6 | Litcius