An Overview of Alphafold's Breakthrough
Ştefan-Bogdan Marcu, Sabin Tăbîrcă, Mark Tangney
Abstract
This paper presents a short summary of the protein folding problem, what it is and why it is significant. Introduces the CASP competition and how accuracy is measured. Looks at different approaches for solving the problem followed by a review of the current breakthroughs in the field introduced by AlphaFold 1 and AlphaFold 2.
Topics & Concepts
CASPCompetition (biology)Field (mathematics)Current (fluid)Folding (DSP implementation)Data scienceComputer scienceManagement scienceProtein structure predictionEngineeringPhysicsMathematicsBiologyEcologyMechanical engineeringProtein structureElectrical engineeringNuclear magnetic resonancePure mathematicsProtein Structure and DynamicsEnzyme Structure and FunctionAlgorithms and Data Compression