Transmission Potential of Asymptomatic and Paucisymptomatic Severe Acute Respiratory Syndrome Coronavirus 2 Infections: A 3-Family Cluster Study in China
Xiaolin Jiang, Xiaoli Zhang, Xiang-Na Zhao, Cun-Bao Li, Jie Lei, Zengqiang Kou, Wenkui Sun, Hang Yang, Feng Gao, Shengxiang Ji, Can-Fang Lin, Bo Pang, Mingxiao Yao, Benjamin D. Anderson, Guolin Wang, Yao Lin, Li‐Jun Duan, Dianmin Kang, Mai‐Juan Ma
Abstract
Data concerning the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in asymptomatic and paucisymptomatic patients are lacking. We report a 3-family cluster of infections involving asymptomatic and paucisymptomatic transmission. Eight of 15 (53%) members from 3 families were confirmed with SARS-CoV-2 infection. Of 8 patients, 3 were asymptomatic and 1 was paucisymptomatic. An asymptomatic mother transmitted the virus to her son, and a paucisymptomatic father transmitted the virus to his 3-month-old daughter. SARS-CoV-2 was detected in the environment of 1 household. The complete genomes of SARS-CoV-2 from the patients were > 99.9% identical and were clustered with other SARS-CoV-2 sequences reported from China and other countries.