Functional sensitivity and mutational robustness of proteins
Qian-Yuan Tang, Tetsuhiro Hatakeyama, Kunihiko Kaneko
Abstract
This paper studies the compatibility of the functional sensitivity and mutational robustness of proteins. The interplay of the two aspects leads to power-law distributions in the vibration spectra of proteins.
Topics & Concepts
Robustness (evolution)Computational biologyComputer scienceBiological systemBiologyGeneticsGeneProtein Structure and DynamicsRNA and protein synthesis mechanismsComputational Drug Discovery Methods