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Coenzyme Q<sub>0</sub> inhibited the NLRP3 inflammasome, metastasis/EMT, and Warburg effect by suppressing hypoxia-induced HIF-1α expression in HNSCC cells

Hsin‐Ling Yang, Che-Wei Chang, Chithravel Vadivalagan, Sudhir Pandey, Siang-Jyun Chen, Chuan-Chen Lee, Jhih‐Hsuan Hseu, You-Cheng Hseu

2024International Journal of Biological Sciences26 citationsDOIOpen Access PDF

Abstract

for the therapeutic application against HNSCC.

Topics & Concepts

Warburg effectGlycolysisAnaerobic glycolysisGLUT1Hypoxia (environmental)Cancer researchBiologyChemistryGlucose transporterBiochemistryEndocrinologyMetabolismInsulinOrganic chemistryOxygenCoenzyme Q10 studies and effectsMitochondrial Function and PathologyAlgal biology and biofuel production
Coenzyme Q<sub>0</sub> inhibited the NLRP3 inflammasome, metastasis/EMT, and Warburg effect by suppressing hypoxia-induced HIF-1α expression in HNSCC cells | Litcius