Synthesis of ester-containing phenanthridines<i>via</i>photoredox-catalyzed radical cascade cyclization of<i>N</i>-arylacrylamides with alkyloxalyl chlorides
Meiling Chen, Jian‐Qiang Chen, Zhengkai Chen, Jie Wu
Abstract
An alkoxycarbonyl-radical-triggered cascade cyclization reaction of N -( o -cyanobiaryl)acrylamides with alkyloxalyl chlorides is developed, leading to diverse ester-containing phenanthridines.
Topics & Concepts
ChemistryCascadeRadical cyclizationCatalysisMedicinal chemistryPhotoredox catalysisOrganic chemistryCombinatorial chemistryPhotocatalysisChromatographyRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques