The role of diffuse correlation spectroscopy and frequency-domain near-infrared spectroscopy in monitoring cerebral hemodynamics during hypothermic circulatory arrests
Alexander I. Zavriyev, Kutlu Kaya, Parisa Farzam, Parya Farzam, John Sunwoo, Arminder S. Jassar, Thoralf M. Sundt, Stefan A. Carp, Maria Angela Franceschini, Jason Zhensheng Qu
Abstract
OBJECTIVES: Real-time noninvasive monitoring of cerebral blood flow (CBF) during surgery is key to reducing mortality rates associated with adult cardiac surgeries requiring hypothermic circulatory arrest (HCA). We explored a method to monitor cerebral blood flow during different brain protection techniques using diffuse correlation spectroscopy (DCS), a noninvasive optical technique which, combined with frequency-domain near-infrared spectroscopy (FDNIRS), also provides a measure of oxygen metabolism. METHODS: ) in 12 patients undergoing cardiac surgery with HCA. RESULTS: . CONCLUSIONS: with intervention and can become a valuable tool for optimizing cerebral protection during HCA.