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Outcome of elexacaftor/tezacaftor/ivacaftor therapy in patients with cystic fibrosis and solid organ transplantation

Matilde Ørum, Frederikke F. Rönsholt, Majbritt Jeppesen, Elisabeth Bendstrup, Terese L. Katzenstein, Peter Ott, Michael Perch, Tacjana Pressler, Tavs Qvist, Søren Jensen‐Fangel

2022Pediatric Pulmonology10 citationsDOI

Abstract

We report a case series of four patients with cystic fibrosis (CF) and previous solid organ transplantation (SOT) receiving elexacaftor/tezacaftor/ivacaftor therapy for 6 months or more. Data was collected retrospectively. The treatment was well tolerated and all patients reported subjective improvements.

Topics & Concepts

IvacaftorMedicineCystic fibrosisTransplantationOrgan transplantationLung transplantationIntensive care medicineInternal medicineCystic fibrosis transmembrane conductance regulatorCystic Fibrosis Research AdvancesTracheal and airway disordersNeonatal Respiratory Health Research
Outcome of elexacaftor/tezacaftor/ivacaftor therapy in patients with cystic fibrosis and solid organ transplantation | Litcius