Systematic reconstruction of molecular pathway signatures using scalable single-cell perturbation screens
Longda Jiang, Carol Dalgarno, Efthymia Papalexi, Isabella Mascio, Hans‐Hermann Wessels, Huiyoung Yun, Nika Iremadze, Gila Lithwick‐Yanai, Doron Lipson, Rahul Satija
Topics & Concepts
Cell biologyScalabilityComputational biologyCellPerturbation (astronomy)ChemistryBiologyBiophysicsComputer scienceBiochemistryPhysicsDatabaseQuantum mechanicsSingle-cell and spatial transcriptomicsCell Image Analysis TechniquesCRISPR and Genetic Engineering