Outer retinal transduction by AAV2-7m8 following intravitreal injection in a sheep model of CNGA3 achromatopsia
Maya Ross, Alexey Obolensky, Edward Averbukh, Mélissa Desrosiers, Raaya Ezra-Elia, Hen Honig, Esther Yamin, A. Rosov, Hay Dvir, E. Gootwine, Eyal Banin, Deniz Dalkara, Ron Ofri
Topics & Concepts
AchromatopsiaPhotopic visionTransduction (biophysics)BiologyTransgeneRetinalRetinaGenetic enhancementGene deliveryOphthalmologyMedicineGeneticsGeneNeuroscienceBiochemistryRetinal Development and DisordersOcular Disorders and TreatmentsCRISPR and Genetic Engineering