M1-like TAMs are required for the efficacy of PD-L1/PD-1 blockades in gastric cancer
Rui Zhao, Qianyi Wan, Yong Wang, Yutao Wu, Shuomeng Xiao, Qiqi Li, Xiaoding Shen, Wen Zhuang, Yong Zhou, Lin Xia, Yinghan Song, Yi Chen, Hanshuo Yang, Xiaoting Wu
Abstract
macrophages are required for the efficacy of PD-L1/PD-1 blockades and expand the applicable candidates in GC patients without the molecular subtypes.
Topics & Concepts
PD-L1Cancer researchCancerCXCL9CD163CD68Immune systemImmunotherapyBiologyGeneImmunologyMedicineImmunohistochemistryInternal medicinePhenotypeChemokineGeneticsCXCL10Immune cells in cancerCancer Immunotherapy and BiomarkersImmune Cell Function and Interaction