Dynamic monitoring of circulating tumor DNA to predict prognosis and efficacy of adjuvant chemotherapy after resection of colorectal liver metastases
De‐Shen Wang, Hui Yang, Xiaoyun Liu, Zhigang Chen, Yun Wang, William Pat Fong, Ming-Tao Hu, Yuanchao Zheng, Yun Zheng, Binkui Li, Yunfei Yuan, Gong Chen, Zhizhong Pan, Lele Song, Yuhong Li, Rui‐Hua Xu
Abstract
We envision that dynamic ctDNA analysis, especially in a post-ACT setting, might be used to not only reflect MRD but also to determine rational personalized adjuvant therapy after the resection of CRLM.
Topics & Concepts
MedicineColorectal cancerChemotherapyOncologyResectionAdjuvant chemotherapyInternal medicineAdjuvantCirculating tumor DNACancer researchCancerSurgeryBreast cancerCancer Genomics and DiagnosticsHepatocellular Carcinoma Treatment and PrognosisRadiomics and Machine Learning in Medical Imaging