Mechanotransduction is a context-dependent activator of TGF-β signaling in mesenchymal stem cells
Steven Vermeulen, Nadia Roumans, Floris Honig, Aurélie Carlier, Dennie G.A.J. Hebels, Aysegul Dede Eren, Peter ten Dijke, Aliaksei Vasilevich, Jan de Boer
Topics & Concepts
MechanotransductionSMADCell biologyMesenchymal stem cellSignal transductionSerum Response ElementTransforming growth factorEGR1MechanobiologyBiologyActivator (genetics)Transforming growth factor betaPhosphorylationGene expressionSerum response factorGeneGeneticsCellular Mechanics and InteractionsHippo pathway signaling and YAP/TAZAxon Guidance and Neuronal Signaling