Arylthianthrenium Salts as the Aryl Sources: Visible Light/Copper Catalysis-Enabled Intermolecular Azidosulfonylation of Alkenes
Hao Xu, Xufeng Li, Yifei Wang, Xiuyan Song, Yongjia Shi, Jian Lv, Daoshan Yang
Abstract
The difunctionalization of alkenes using aryl thianthrenium salts as the aryl sources has been reported sporadically. However, the four-component difunctionalization of alkenes on the basis of aryl thianthrenium salts has not been reported thus far and still remains a challenge. Herein, a visible light/copper catalysis-enabled four-component reaction of aryl thianthrenium salts, DABCO·(SO 2 ) 2, alkenes, and TMSN 3 is presented, which affords a facile approach to β-azidosulfones in good yields with broad substrate scope and excellent functional group tolerance. This strategy indirectly realizes the method for the synthesis of β-azidosulfones through site-selective aryl C–H bond functionalization and alkene difunctionalization. This developed method is an important complement to thianthrenium salts chemistry.