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Transport of drugs using complex peristaltic waves in a biological system

Nouman Ijaz, A. Zeeshan, Arshad Riaz, Mohammed Sh. Alhodaly

2022Waves in Random and Complex Media39 citationsDOI

Abstract

Targeted drugging in view of diseases, such as cancer, diabetes, and cardiovascular diseases. etc., has become vitally important. This theoretical analysis intricates the transport of drugs using Peristaltic micro-pumps and is controlled by a magnetic field in pharmacological engineering. The current article analyzed small drug particles embedded in a non-Newtonian fluid in a partially permeable space enclosed between flexible walls. To control the transport process magnetic force lines are applied at a right angle to the flow direction. The transportation of liquid along with drug particles due to the peristaltic movement of walls of a channel is modeled, simulated, and analyzed. Considering the flow assumptions and conditions, a second-order system of partial differential equations (PDEs) is devised to describe the flow. The numerical simulation using pdepe is established and graphically displayed for the effects of different parameters.

Topics & Concepts

PeristalsisMechanicsPhysicsPeristaltic pumpClassical mechanicsMathematical analysisMathematicsThermodynamicsMedicineAnatomyField-Flow Fractionation TechniquesAcoustic Wave Resonator TechnologiesNanopore and Nanochannel Transport Studies
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