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Biotin-conjugated Ru(II) complexes with AIE characteristics as mitochondria-targeted photosensitizers for enhancing photodynamic therapy by disrupting cellular redox balance

Lai Wei, Xiangdong He, Deming Zhao, Martha Kandawa-Shultz, Guoqiang Shao, Yihong Wang

2023European Journal of Medicinal Chemistry18 citationsDOI

Topics & Concepts

ChemistrySinglet oxygenPhototoxicityPhotodynamic therapyReactive oxygen speciesA549 cellPhotochemistryPhotosensitizerApoptosisBiophysicsQuenching (fluorescence)DNA damageIntracellularRedoxFluorescenceDNAOxygenBiochemistryIn vitroQuantum mechanicsOrganic chemistryBiologyPhysicsNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsAdvanced biosensing and bioanalysis techniques
Biotin-conjugated Ru(II) complexes with AIE characteristics as mitochondria-targeted photosensitizers for enhancing photodynamic therapy by disrupting cellular redox balance | Litcius