Utilizing a Dual Human Transporter MDCKII-MDR1-BCRP Cell Line to Assess Efflux at the Blood Brain Barrier
Nicola Colclough, Ravindra V. Alluri, James W. Tucker, Elnaz Gozalpour, Danxi Li, Hongwen Du, Wei Li, Stephanie Harlfinger, Daniel O’Neill, Graham Sproat, Kan Chen, Yumei Yan, Dermot F. McGinnity
Topics & Concepts
EffluxBlood–brain barrierPharmacologyAbcg2TransporterDual (grammatical number)ChemistryATP-binding cassette transporterBiologyCentral nervous systemGeneBiochemistryNeuroscienceLiteratureArtDrug Transport and Resistance MechanismsMetabolism and Genetic DisordersNeonatal Health and Biochemistry