Epigenetic silencing of chemokine CCL2 represses macrophage infiltration to potentiate tumor development in small cell lung cancer
Yang Zheng, Zhihong Wang, Simeng Wei, Ziling Liu, Guojiang Chen
Topics & Concepts
Cancer researchCCL2BiologyChemokineDNA methylationEctopic expressionEpigeneticsDecitabineDNMT1Gene silencingMacrophageInnate immune systemEZH2ImmunologyCell cultureInflammationImmune systemGene expressionIn vitroGeneBiochemistryGeneticsImmune cells in cancerLung Cancer Research StudiesEpigenetics and DNA Methylation