Litcius/Paper detail

EGFR-targeted prodrug activation using bioorthogonal alkene-azide click-and-release chemistry

Jessica M. Fairhall, Júlia Constantino Camilli, Blake Gibson, Sarah Hook, Allan B. Gamble

2021Bioorganic & Medicinal Chemistry16 citationsDOI

Topics & Concepts

Bioorthogonal chemistryProdrugChemistryClick chemistryDoxorubicinCetuximabEpidermal growth factor receptorCancer researchCombinatorial chemistryBiochemistryMonoclonal antibodyAntibodyReceptorChemotherapyImmunologyBiologyMedicineInternal medicineClick Chemistry and ApplicationsMonoclonal and Polyclonal Antibodies ResearchProtein Degradation and Inhibitors