Litcius/Paper detail

Polarisation effects on the H-bond acceptor properties of secondary amides

Fergal E. Hanna, Alexander J. Root, Christopher A. Hunter

2023Chemical Science13 citationsDOIOpen Access PDF

Abstract

measured for the secondary amide H-bond donor and H-bond acceptor is identical, which implies that polarisation of an amide mediates the interaction between an external donor or acceptor in a reciprocal manner.

Topics & Concepts

ChemistryIntramolecular forceCooperativityAcceptorPyridineAmideIntermolecular forceHydrogen bondCrystallographyElectron acceptorMoleculePhotochemistryStereochemistryMedicinal chemistryOrganic chemistryBiochemistryCondensed matter physicsPhysicsMolecular spectroscopy and chiralityCrystallography and molecular interactionsAnalytical Chemistry and Chromatography